Oroxylum
At a glance
- Best for
- adults curious about a flavonoid-rich nootropic, accepting thin evidence
- Typical dose
- About 500 mg/day of standardized bark extract
- Time to effect
- Weeks
- Main caution
- Limited human safety data; quality and standardization vary
What is it
Oroxylum (Oroxylum indicum), the Indian trumpet tree, is an Ayurvedic botanical whose bark and seeds are rich in flavonoids such as baicalein, chrysin and oroxylin A. It is sold as standardized extracts (e.g. Sabroxy) marketed for mood and cognition. Human evidence is early and limited to a small number of trials.
Is it worth it for you?
Worth considering if…
- You want to experiment with a flavonoid nootropic and track your own response
- You can source a standardized, third-party-tested extract
Probably skip if…
- You want established cognitive benefits
- You are pregnant, breastfeeding, or on multiple medications
- You expect a clear, reliable effect
Evidence at a glance
| Goal | Evidence | Effect | Best fit | Time |
|---|---|---|---|---|
| cognition and mood support | Limited Evidence | Small/uncertain | healthy adults seeking mild cognitive or mood support | Weeks |
Evidence for 1 use
AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.
cognition and mood support
Supplement benefitStandardized Oroxylum bark extract has been tested in a small number of human trials for memory and mood, with flavonoids like baicalein and oroxylin A showing neuroactive effects in preclinical models. The clinical data are preliminary, with few participants and limited replication. Any benefit appears modest and is not yet well established.
Bottom line: Early human data hint at mild cognitive support, but evidence is too thin to rely on.
Evidence is mixed
Only a handful of small trials exist and most supporting data are preclinical, so confidence is low.
How to take it
- Typical dose
- ~500 mg/day standardized bark extract
- Timing
- Morning or with a meal
- With food
- With food
- How long to try
- Trial 8–12 weeks and reassess
What to track
- Subjective focus and mood
- Sleep quality
- Any GI upset or headache
Safety
Common side effects
Mild GI upset, Headache
Who should avoid it
- Pregnant or breastfeeding people
- People on sedatives or psychiatric medication without medical advice
Pregnancy & breastfeeding
Avoid in pregnancy and breastfeeding; safety has not been established.
Interactions
Flavonoids may have additive central effects; data are limited
Choosing a product
Look for
- Species Oroxylum indicum identified
- Standardized flavonoid content (e.g. baicalein)
- Stated plant part (bark) and third-party testing
Be skeptical of
- Boosts IQ
- Treats depression or anxiety
- Clinically proven brain booster
References by claim
cognition and mood support
- Lopresti et al., 2021 — PMC (2021) link
Track Oroxylum with Pilora
Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.
Coming to App StoreDisclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.