Evidence-based·Last reviewed May 30, 2026·How we grade evidence

Sea Buckthorn

BotanicalBest with a meal

Useful mainly for people with dryness of the eyes or mucous membranes seeking a nutritional oil.

Quick decision guide

May help most

people with dryness of the eyes or mucous membranes seeking a nutritional oil

Common dosing range

1.5–3 g/day of sea buckthorn oil

When to expect effects

Weeks

Watch out for

may add to bleeding risk with anticoagulants; acidic berries can aggravate reflux

What is it

Sea buckthorn (Hippophae rhamnoides) is a hardy shrub native to Europe and Asia whose bright orange berries are unusually rich in vitamin C, carotenoids, vitamin E, and rare omega-7 fatty acids. The berries, seeds, and seed oil are used as foods and supplements.

Is it worth it for you?

Use this as a quick fit check, not a diagnosis.

Worth considering if

you have dry eye or mucosal dryness and want a well-tolerated oil to try
you choose a fresh, properly stored oil (it oxidizes easily)
you take it with a fat-containing meal for absorption

Probably skip if

you expect a strong or fast effect on dryness
you take anticoagulants and cannot check with a clinician
you want proven cardiovascular or skin-disease treatment

Evidence at a glance

dry eye syndrome

Limited Evidence
Effect
Small
Best fit
people with mild dry eye, including in dry seasons
Time
Weeks

mucosal and vaginal dryness

Limited Evidence
Effect
Modest
Best fit
postmenopausal women or others with mucosal dryness
Time
Weeks

skin conditions (eczema, dryness)

Mixed Evidence
Effect
Not established
Best fit
not established
Time
Weeks

Evidence for 3 uses

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

dry eye syndrome

Supplement benefit
Limited Evidence

A randomized trial of sea buckthorn oil reported reduced worsening of dry-eye symptoms and signs over a dry-season period, attributed partly to its omega-7 (palmitoleic) and omega-3 fatty acids. Evidence is limited to a few small studies and effects are modest.

Effect size
Small
Time to effect
Weeks
Best fit
people with mild dry eye, including in dry seasons

Bottom line: May modestly ease dry-eye symptoms, but the supporting evidence is small and limited.

mucosal and vaginal dryness

Supplement benefit
Limited Evidence

A small randomized trial found oral sea buckthorn oil improved vaginal epithelial integrity and dryness in postmenopausal women, again linked to its omega-7 fatty acid content and a proposed role in mucosal membrane health. The evidence base is small and preliminary.

Effect size
Modest
Time to effect
Weeks
Best fit
postmenopausal women or others with mucosal dryness

Bottom line: Limited evidence suggests it may help mucosal dryness, but trials are small.

skin conditions (eczema, dryness)

Supplement benefit
Mixed Evidence

Sea buckthorn oil's fatty acids and antioxidants are used in skin formulations, and small studies suggest possible benefit for dry skin and certain inflammatory dermatoses such as atopic dermatitis. Trials are few, small, and inconsistent, so benefit is unproven.

Effect size
Not established
Time to effect
Weeks
Best fit
not established

Bottom line: Possible but unproven help for dry or inflamed skin; evidence is weak.

How it works

Sea buckthorn's nutritional density is its main pharmacological asset. The berry pulp oil is one of the only plant sources of palmitoleic acid (an omega-7 fatty acid), which research suggests plays a role in mucosal membrane health. The seed oil contains a balanced ratio of omega-3 (alpha-linolenic acid) and omega-6 (linoleic acid) fatty acids. The berries are also high in flavonoids (quercetin, isorhamnetin, kaempferol), carotenoids (beta-carotene, lycopene, zeaxanthin), tocopherols (vitamin E), and ascorbic acid (vitamin C), often at levels exceeding those of citrus. These antioxidants may help mitigate oxidative stress in cell models, though clinical translation is less clear. Topically, sea buckthorn oil is incorporated into skin formulations for its fatty acid and antioxidant content, with limited evidence supporting use in dry skin and certain inflammatory dermatoses.

How to take it

1. Typical dose
1.5–3 g/day of sea buckthorn oil (seed or pulp); 10–28 g/day of berry pulp or juice in some studies
2. Timing
any time; effects build over weeks
3. With food
with a meal containing fat for the oil to absorb
4. How long to try
trial for 1–3 months for dryness outcomes

What to track

eye comfort and dryness
mucosal dryness symptoms
GI tolerance/reflux
skin hydration if used for skin

3 commercial forms

Compare the main delivery options and what they’re best suited for.

Berry pulp oil

The orange-red oil pressed from the fruit pulp. Often emphasized for mucosal and skin support due to omega-7 content.

Rich in palmitoleic acid (omega-7) and carotenoids; fat-soluble.

Seed oil

Pressed from the seeds, with higher proportions of alpha-linolenic and linoleic acids and lower carotenoid content than pulp oil.

Balanced omega-3 and omega-6 fatty acids; fat-soluble.

Juice or whole berry powder

Used as a vitamin C and antioxidant-rich food ingredient. Tart, sour taste; commonly blended with other juices.

Water-soluble vitamin C and flavonoids retained.

Safety

Know the common side effects, key cautions, and who should avoid it.

Common side effects

mild GI upsetreflux from acidic berriesrare allergic reactions

Who should avoid it

  • people on anticoagulants or with bleeding disorders without clinician input
  • those within 1–2 weeks of surgery

Pregnancy & breastfeeding

Consult a clinician before using concentrated supplements in pregnancy or breastfeeding, as data are limited.

Interactions

anticoagulants and antiplatelet drugs (warfarin, aspirin)Moderate

flavonoids may add to bleeding risk

antihypertensive drugsMinor

possible additive blood-pressure lowering (animal data)

Choosing a product

What to look for on the label — and what to be skeptical of.

Look for

fresh, well-stored oil with antioxidant protection
specifies seed vs pulp oil
named species (Hippophae rhamnoides)

Be skeptical of

miracle skin healer
anti-aging cure
treats heart disease

Frequently asked questions

What is omega-7 and why is sea buckthorn known for it?

Omega-7 (palmitoleic acid) is a fatty acid found in few foods. Sea buckthorn pulp oil is one of the highest plant sources, which is why it is often marketed for mucosal membrane health.

How is the seed oil different from the pulp oil?

Pulp oil is orange and rich in carotenoids and omega-7. Seed oil is a paler yellow and is dominated by omega-3 and omega-6 fatty acids. Products may blend both or list which one is included.

Is sea buckthorn high in vitamin C?

Yes. The berries contain substantially more vitamin C by weight than oranges, though the exact amount depends on cultivar and processing.

Can I apply sea buckthorn oil to my skin?

Yes. It is widely used in skincare for moisturization and as a carrier oil. Test on a small patch first, as the deep orange color can temporarily stain skin and fabric.

References by claim

dry eye syndrome

Larmo et al., 2019PubMed (2019) link

Järvinen et al., 2011PubMed (2011) link

mucosal and vaginal dryness

Larmo et al., 2014PubMed (2014) link

skin conditions (eczema, dryness)

Yang et al., 1999PubMed (1999) link

Track Sea Buckthorn with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

Coming to App Store
Evidence-based·Last reviewed May 30, 2026·Evidence current as of May 30, 2026·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.