Myrrh

botanical

At a glance

Best for
topical/oral use for mouth and gum irritation; investigational antiparasitic use
Typical dose
Mouth rinse or local application; oral antiparasitic dosing per specific product
Time to effect
Days for local oral symptoms
Main caution
may stimulate the uterus and affect bleeding and blood sugar; avoid in pregnancy
Evidence strength: Limited; small or contested trials

What is it

Myrrh is the dried oleo-gum-resin of Commiphora trees (notably Commiphora myrrha/molmol), used since antiquity as an aromatic, an oral antiseptic, and a wound and gum remedy. Modern interest centers on its use as a mouth rinse and as an antiparasitic agent (the drug Mirazid), though clinical evidence is limited and contested.

Is it worth it for you?

Worth considering if…

  • you want a traditional rinse for sore gums or minor mouth irritation
  • you tolerate it and are not pregnant

Probably skip if…

  • you are pregnant or breastfeeding
  • you expect a reliable cure for parasitic infection (efficacy is disputed)
  • you take anticoagulants or have poorly controlled diabetes

Evidence at a glance

GoalEvidenceEffectBest fitTime
mouth and gum irritation (oral antiseptic)LimitedModest local effectadults with sore gums, mouth ulcers, or minor oral inflammationDays
parasitic infection (schistosomiasis/fascioliasis, investigational)MixedDisputedinvestigational use only in endemic-disease settingsDays to weeks

Evidence for 2 uses

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

mouth and gum irritation (oral antiseptic)

Supplement benefit
Limited

Myrrh has astringent and antimicrobial properties and is a long-standing ingredient in mouthwashes and gum preparations, sometimes combined with chamomile. Small studies and traditional use support a soothing local effect on mouth ulcers and gingival irritation, but rigorous, well-powered trials are lacking.

Effect size: Modest local effect
Time to effect: Days
Best fit: adults with sore gums, mouth ulcers, or minor oral inflammation

Bottom line: Reasonable as a traditional oral rinse for minor gum and mouth irritation, with limited trial support.

parasitic infection (schistosomiasis/fascioliasis, investigational)

Disease adjunct
Mixed

A myrrh extract drug (Mirazid) was promoted in Egypt for schistosomiasis and fascioliasis, with early studies reporting high cure rates. Subsequent independent trials found markedly lower and inconsistent efficacy compared with standard drugs such as praziquantel, leaving its antiparasitic value unconfirmed.

Effect size: Disputed
Time to effect: Days to weeks
Best fit: investigational use only in endemic-disease settings

Bottom line: Antiparasitic use is unproven and inferior to standard therapy in independent studies.

Evidence is mixed

Initial Egyptian trials reported high cure rates, but independent replications showed much weaker and inconsistent efficacy versus established antiparasitic drugs.

How to take it

Typical dose
As a diluted mouth rinse or local gum application; oral antiparasitic use only under a specific product/protocol
Timing
after brushing for oral use
With food
rinse use is independent of food
How long to try
Short-term for oral symptoms

What to track

  • gum soreness or mouth ulcer healing
  • any GI upset with oral use

Safety

Common side effects

GI upset with oral use, mild local irritation in the mouth

Serious risks

Who should avoid it

Pregnancy & breastfeeding

Avoid; myrrh may stimulate uterine contractions.

Interactions

warfarin and other anticoagulantsModerate

may affect bleeding; theoretical additive risk

antidiabetic drugsMinor

may lower blood glucose; monitor for additive effect

Choosing a product

Look for

  • identifies Commiphora species and resin source
  • clear directions distinguishing rinse vs oral use

Be skeptical of

  • claims to cure parasites or worms
  • cancer treatment claims
  • internal-use safety claims during pregnancy

References by claim

mouth and gum irritation (oral antiseptic)

  • Mansour et al., 2014PubMed (2014) link
  • Ibraheem et al., 2022PMC (2022) link

parasitic infection (schistosomiasis/fascioliasis, investigational)

  • Osman et al., 2010PubMed (2010) link
  • Soliman et al., 2004PubMed (2004) link

Safety

  • Memorial Sloan Kettering — MyrrhMSKCC About Herbs link

Track Myrrh with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

Coming to App Store
Evidence-based·Last reviewed May 30, 2026·Evidence current as of May 30, 2026·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.