Eriocitrin

PhytochemicalFlavanone glycosideBest with a meal

What is it

Eriocitrin is a citrus flavonoid (flavanone glycoside) found primarily in lemons. It is the most abundant flavonoid in lemon juice and peel and is used as an antioxidant and metabolic support supplement.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Metabolic support / glucose

Limited Evidence

Small human trials show modest improvements in markers of glucose metabolism and oxidative stress. Evidence is preliminary.

How it works

After ingestion, eriocitrin is converted to eriodictyol and related metabolites by gut bacteria. These compounds have antioxidant activity, may modulate PPAR signaling, and influence lipid metabolism. Animal studies suggest potential benefits in metabolic syndrome, but human data are limited. A few human trials with concentrated lemon flavonoid products (such as Eriomin) have suggested improvements in fasting glucose and oxidative stress markers, though evidence is still emerging.

Dosage

Most studies use 100-200 mg of eriocitrin per day. Optimal dosing is not yet established.

When and how to take it

WHEN: Once daily with food. HOW: With water and a meal.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Standardized eriocitrin extract

Concentrated lemon flavonoid extract.

Branded extracts (Eriomin) used in clinical trials.

Safety

Well tolerated in short-term human trials. No serious adverse effects reported. Long-term safety data are limited.

Who should be cautious

Limited safety data in pregnancy and breastfeeding. Discuss with clinician if you have diabetes.

Interactions

No significant interactions reported. May modestly affect blood glucose; monitor if on antidiabetic medications.

Food sources

Lemon

Amount
1 medium fruit
%DV
—

Frequently asked questions

Is eriocitrin the same as hesperidin?⌄

Both are citrus flavonoids but they are different compounds. Hesperidin is more abundant in oranges; eriocitrin is more abundant in lemons.

References

Eriocitrin on Wikidata — Wikidata link

Eriocitrin on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Eriocitrin (PubMed search) — PubMed link

Track Eriocitrin with Pilora

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.