Betuligneol

PhytochemicalLignan

What is it

Betuligneol is a lignan-related compound found in birch (Betula species). It is one of several phenolic compounds in birch bark and leaves.

How it works

Birch lignans have been studied for antioxidant and anti-inflammatory activity in laboratory settings. Specific human clinical data on isolated betuligneol are not available; supplement use typically involves whole birch extracts.

Dosage

No standardized supplement dose. Birch extracts vary in concentration of specific compounds.

When and how to take it

No formal timing guidance.

1 commercial form

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Birch bark or leaf extract

Primary source of betuligneol in supplements.

Phenolic absorption is moderate

Safety

Limited published human safety data for isolated betuligneol. Birch extracts are generally well tolerated; birch pollen allergy may produce cross-reactions with bark and leaf products.

Who should be cautious

Avoid in pregnancy, breastfeeding, and birch allergy. Use caution if allergic to related birch family plants.

Interactions

No significant interactions reported in available literature.

Frequently asked questions

What is betuligneol?⌄

A phenolic compound from birch (Betula) species.

Is it safe?⌄

Birch extracts are generally tolerated at typical doses. Avoid in birch allergy.

References

Betuligneol on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Betuligneol (PubMed search) — PubMed link

Track Betuligneol with Pilora

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.