Saccharomyces Boulardii Interactions

Saccharomyces boulardii is a live yeast that is directly susceptible to systemic antifungals such as fluconazole, itraconazole, amphotericin B, and echinocandins, which kill the probiotic and negate its benefit. The same antifungals may be required to treat S. boulardii fungemia, a documented complication in critically ill and immunocompromised patients.