Blood Pressure Medications Interactions

Celery contains phthalides (including 3-n-butylphthalide), nitrate, and other constituents that relax vascular smooth muscle and have demonstrated blood pressure lowering effects in animal and small human studies. Large daily celery juice intake can add to the effect of antihypertensive drugs, including ACE inhibitors, calcium channel blockers, and diuretics.

Dark chocolate flavanols improve nitric-oxide-dependent vasodilation and modestly lower systolic and diastolic blood pressure (typically 2–3 mmHg). Combined with antihypertensives, this can additively lower blood pressure, occasionally producing symptoms of hypotension such as dizziness in sensitive patients.