Bananas Interactions

Bananas are a high-potassium food (around 422 mg per medium banana), and spironolactone is a potassium-sparing diuretic that reduces renal potassium excretion. Combining high dietary potassium with spironolactone can cause hyperkalemia, which may trigger dangerous cardiac arrhythmias.

Lisinopril is an ACE inhibitor that reduces aldosterone and increases serum potassium. Combined with high dietary potassium from bananas and other potassium-rich foods, this can cause hyperkalemia, particularly in patients with reduced kidney function or those also taking potassium-sparing diuretics.