Uva Ursi

botanicalleaf extract

At a glance

Best for
adult women with an acute uncomplicated lower UTI, short-term only
Typical dose
400-840 mg arbutin/day, divided
Time to effect
Days
Main caution
limit to under 1-2 weeks per course due to hydroquinone exposure
Evidence strength: Limited; small/older trials for acute UTI

What is it

Uva ursi, also known as bearberry, is the leaf of Arctostaphylos uva-ursi , a low-growing evergreen shrub of cold-temperate Northern Hemisphere regions. The leaves contain 5-15% arbutin (a hydroquinone glucoside), tannins (gallotannins and ellagitannins, often 6-20%), iridoids, and flavonoids. Arbutin is the principal active and is hydrolysed in vivo - particularly in alkaline urine - to release hydroquinone, which exerts mild antibacterial activity in the urinary tract; this mechanism underlies the historical and modern herbal use of uva ursi as a treatment for uncomplicated lower urinary tract infections in adult women.

Is it worth it for you?

Worth considering if…

  • You are an adult woman with an acute uncomplicated lower UTI
  • You want a short-course herbal option
  • You will keep use under one week per course

Probably skip if…

  • You need long-term or prophylactic use
  • You are pregnant, breastfeeding, or under 12
  • You have renal impairment or signs of an upper UTI

Evidence at a glance

GoalEvidenceEffectBest fitTime
acute uncomplicated lower urinary tract infectionMixedUncertain; small studiesAdult women with acute uncomplicated lower UTI seeking a short-course optionDays

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

acute uncomplicated lower urinary tract infection

Disease adjunct
Mixed

Arbutin in uva ursi is hydrolyzed in vivo, especially in alkaline urine, to hydroquinone, which has mild urinary antibacterial activity underlying its traditional and monograph-supported use. Clinical evidence is limited to small and older trials, and use must be short because of hydroquinone exposure concerns.

Effect size: Uncertain; small studies
Time to effect: Days
Best fit: Adult women with acute uncomplicated lower UTI seeking a short-course option
Less likely: People with upper UTI, fever, or complicated infection

Bottom line: A short-course herbal option for acute lower UTI in women, with limited trial support.

How to take it

Typical dose
400-840 mg arbutin/day (about 3-4 g dried leaf or equivalent extract), divided into 2-3 doses
Timing
Spread across the day
With food
Note tannins with meals can reduce iron and alkaloid absorption
How long to try
No more than 1 week per course and no more than 5 courses per year

What to track

  • UTI symptoms (dysuria, frequency)
  • Any fever or flank pain (seek care)
  • GI tolerance

Safety

Common side effects

Mild nausea, Gastric irritation, Greenish urine discoloration

Serious risks

  • Potential hepatotoxicity and theoretical genotoxicity from hydroquinone with high doses or prolonged use

Who should avoid it

  • Pregnant or breastfeeding people
  • Children under 12
  • People with renal impairment

Pregnancy & breastfeeding

Contraindicated in pregnancy and lactation due to possible oxytocic effects and lack of safety data.

Interactions

Non-heme iron and alkaloidal drugsMinor

Tannins can reduce absorption when taken together

Choosing a product

Look for

  • Standardized arbutin content
  • Clear short-course dosing instructions
  • Leaf (Arctostaphylos uva-ursi) source

Be skeptical of

  • Safe for long-term daily use
  • Prevents recurrent UTIs

References by claim

acute uncomplicated lower urinary tract infection

  • Gágyor et al., 2021PubMed (2021) link
  • Trill et al., 2017PMC (2017) link

Track Uva Ursi with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

Coming to App Store
Evidence-based·Last reviewed May 30, 2026·Evidence current as of May 30, 2026·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.