Evidence-based·Last reviewed May 30, 2026·How we grade evidence

Ophiopogon

Botanical

Useful mainly for no standalone use is supported by good human trials.

Quick decision guide

May help most

no standalone use is supported by good human trials

Common dosing range

no well-established single-herb clinical dose

When to expect effects

Not established

Watch out for

evidence comes mostly from multi-herb formulas and animal models

What is it

Ophiopogon (Ophiopogon japonicus), known as Mai Dong or dwarf lilyturf, is a plant whose tuberous roots are a common ingredient in traditional Chinese medicine. It is used traditionally to 'moisten' dryness, for cough, and as part of cardiovascular formulas, and contains saponins (ophiopogonins) and polysaccharides. Almost all supporting evidence is preclinical or from multi-herb formulas rather than the isolated herb.

Is it worth it for you?

Use this as a quick fit check, not a diagnosis.

Worth considering if

You are using it within a clinician-guided traditional formula and accept limited evidence

Probably skip if

You want a single-ingredient remedy with proven benefit
You expect cardiovascular or respiratory treatment effects from the isolated herb

Evidence at a glance

cardiovascular support (traditional / formula-based)

Mixed Evidence
Effect
Not established
Best fit
none established for the isolated herb
Time
Not established

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

cardiovascular support (traditional / formula-based)

Mechanism only
Mixed Evidence

Ophiopogon is a component of traditional cardiovascular formulas (such as Sheng Mai San), and animal and cell studies report antioxidant, anti-inflammatory, and myocardial-protective activity for its ophiopogonins and polysaccharides. Human evidence is largely confined to multi-herb formulas, making it impossible to attribute any effect to ophiopogon alone. This is mechanistic and formula-level evidence, not isolated-herb clinical proof.

Effect size
Not established
Time to effect
Not established
Best fit
none established for the isolated herb

Bottom line: Cardiovascular use rests on preclinical data and multi-herb formulas, not on the isolated herb.

How to take it

1. Typical dose
No standardized single-herb dose; traditionally used within decoctions/formulas
2. Timing
Not established
3. With food
Not established
4. How long to try
Not established

What to track

Whatever symptom is targeted
Any GI upset or interactions

Safety

Know the common side effects, key cautions, and who should avoid it.

Common side effects

Generally regarded as well tolerated traditionallyPossible GI upset

Who should avoid it

  • Pregnant or breastfeeding people (insufficient data)
  • Anyone needing evidence-based treatment

Pregnancy & breastfeeding

No reliable safety data in pregnancy or breastfeeding; avoid medicinal use.

Choosing a product

What to look for on the label — and what to be skeptical of.

Look for

Correct species (Ophiopogon japonicus)
Named plant part (root/tuber)
Third-party identity testing

Be skeptical of

Cardiovascular or heart-disease treatment claims
Implied proven benefit from the single herb
'Yin-tonifying cure-all' marketing

References by claim

cardiovascular support (traditional / formula-based)

Chen et al., 2016PubMed (2016) link

Fang et al., 2018PubMed (2018) link

Track Ophiopogon with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

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Evidence-based·Last reviewed May 30, 2026·Evidence current as of May 30, 2026·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.