Motherwort

botanical

At a glance

Best for
people seeking a traditional calming herb for mild palpitations or tension (with caution)
Typical dose
varies widely by preparation; follow product directions
Time to effect
Weeks (uncertain)
Main caution
very limited human evidence and potential cardiac and bleeding effects; not for self-treating heart conditions
Evidence strength: Very limited; mostly traditional use and preclinical data

What is it

Motherwort (Leonurus cardiaca, and the related Chinese Leonurus japonicus) is a mint-family herb traditionally used for heart palpitations, nervous tension, and menstrual and postpartum complaints. It is taken as a tincture, tea, or extract. Human clinical evidence is sparse, and most data come from traditional use and laboratory studies.

Is it worth it for you?

Worth considering if…

  • you are exploring a traditional calming herb under informed caution
  • you accept that human evidence is minimal

Probably skip if…

  • you have a diagnosed heart rhythm or blood-pressure disorder (see a clinician)
  • you are pregnant or trying to conceive
  • you want reliably proven benefits
  • you take anticoagulants or cardiac medications

Evidence at a glance

GoalEvidenceEffectBest fitTime
palpitations and nervous tensionMixedUncertainpeople with mild stress-related palpitations seeking a traditional optionWeeks (uncertain)

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

palpitations and nervous tension

Supplement benefit
Mixed

Motherwort has a long traditional reputation for calming palpitations and nervous tension, and a small open-label study of a Leonurus oil extract reported reduced anxiety and blood pressure in people with hypertension. The evidence is preliminary, uncontrolled, and insufficient to confirm a real effect. Preclinical work suggests mild cardiovascular and sedative actions.

Effect size: Uncertain
Time to effect: Weeks (uncertain)
Best fit: people with mild stress-related palpitations seeking a traditional option

Bottom line: Traditional use and one small uncontrolled study hint at calming and mild cardiovascular effects, but the evidence is too weak to rely on.

Evidence is mixed

Support rests on tradition and a single small uncontrolled study; no robust controlled trials confirm benefit.

How to take it

Typical dose
preparation-dependent; follow the product label, starting low
Timing
as directed, often divided through the day
With food
with food to reduce stomach upset
How long to try
short trial with monitoring

What to track

  • palpitations or heart-rate sensations
  • anxiety or tension
  • blood pressure
  • any unusual bleeding or bruising

Safety

Common side effects

stomach upset, drowsiness, uterine cramping

Serious risks

  • possible effects on heart rhythm and blood pressure
  • possible increased bleeding risk

Who should avoid it

  • pregnant people (may stimulate the uterus)
  • people on anticoagulants or cardiac/blood-pressure medications without supervision
  • people with bradycardia or low blood pressure

Pregnancy & breastfeeding

Avoid in pregnancy; motherwort can stimulate uterine contractions.

Interactions

anticoagulants and antiplateletsModerate

may add to bleeding risk

cardiac and blood-pressure medicationsModerate

may alter heart rate and blood pressure, compounding drug effects

sedativesMinor

possible additive drowsiness

Choosing a product

Look for

  • identifies the species (Leonurus cardiaca or japonicus)
  • states extract strength and part used
  • third-party tested for contaminants

Be skeptical of

  • treats heart disease or arrhythmia
  • safe in pregnancy
  • cures anxiety

References by claim

palpitations and nervous tension

  • Shikov et al., 2011PubMed (2011) link

Track Motherwort with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

Coming to App Store
Evidence-based·Last reviewed May 30, 2026·Evidence current as of May 30, 2026·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.