Magroside

PhytochemicalMogroside

What is it

Magroside is a name used for cucurbitane glycoside compounds from monk fruit (Siraitia grosvenorii), better known by the related name mogrosides. They are intensely sweet compounds used as natural zero-calorie sweeteners.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Sugar substitution

Good Evidence

Monk fruit sweeteners reduce caloric intake when replacing sugar without raising blood glucose.

How it works

Mogrosides (or magrosides) are triterpene glycosides up to 300 times sweeter than sucrose, with mogroside V being the most abundant in commercial extracts. They are not metabolized to glucose and have minimal effect on blood sugar. The FDA has recognized monk fruit extract as GRAS as a sweetener. It does not raise glycemic index, making it suitable for diabetics and people on low-carb diets.

Dosage

Used at sweetening amounts only. Microgram-to-milligram quantities per serving provide intense sweetness.

When and how to take it

Not applicable as a sweetener.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Mogroside V (Magroside V)

Standardized to specific mogroside content in commercial sweeteners.

Minimal absorption.

Safety

Considered safe at typical use levels. No reported toxicity at sweetener doses.

Who should be cautious

No specific cautions identified at typical sweetener use.

Interactions

No significant medication interactions reported.

Food sources

Monk fruit (luo han guo)

Amount
1 fruit
%DV
—

Frequently asked questions

Is magroside the same as monk fruit extract?⌄

Yes. The name refers to the mogroside compounds in monk fruit.

Does monk fruit raise blood sugar?⌄

No. Mogrosides do not affect glucose levels at typical sweetener doses.

References

Magroside on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Magroside (PubMed search) — PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.