Laxosterone

PhytochemicalSpirostanic saponin

What is it

Laxosterone (also called 5-alpha-hydroxy-laxogenin) is a plant-derived spirostanic steroid related to laxogenin, marketed in some bodybuilding supplements as an 'anabolic' compound.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Muscle/strength gains

Mixed Evidence

No high-quality human clinical evidence supports the marketing claims. Mechanistic rationale is weak.

How it works

Laxosterone is structurally similar to plant ecdysteroids and has been promoted with claims of increasing protein synthesis and supporting muscle gain. Mechanistic claims are extrapolated from rodent or in vitro work on related compounds. There are no rigorous human clinical trials demonstrating anabolic effects in people. Some products marketed as 'laxosterone' have been found to contain other undeclared compounds.

Dosage

No established dose. Products typically suggest 25-100 mg/day, but these are not safety-validated.

When and how to take it

Not applicable; not recommended.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Bodybuilding supplement ingredient

Often combined with other 'natural anabolic' claims.

Variable; gray-market products are not quality-controlled.

Safety

Limited human safety data. SARM- and prohormone-labeled products in this category have been linked to liver injury in case reports. Adulteration with other compounds is common in the gray-market supplement space.

Who should be cautious

Avoid in pregnancy, breastfeeding, anyone under 21, and people with liver disease. Banned for some competitive athletes depending on category and governing body.

Interactions

Insufficient data. Avoid combining with hepatotoxic substances (alcohol, acetaminophen) and other anabolic compounds.

Food sources

Not a food source

Amount
N/A
%DV
—

Frequently asked questions

Is laxosterone safe?⌄

Human safety data is limited. Products in this category have a history of adulteration and case reports of liver injury. Caution is warranted.

References

Laxosterone on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Laxosterone (PubMed search) — PubMed link

Track Laxosterone with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.