Lagerstroemin

PhytochemicalEllagitannin

What is it

Lagerstroemin is an ellagitannin found in banaba leaf (Lagerstroemia speciosa). It is one of several active compounds in banaba, alongside corosolic acid, that have been studied for blood-glucose support.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Blood glucose support (banaba extract)

Limited Evidence

Small clinical studies of banaba extract show modest reductions in fasting and postprandial glucose. Evidence specific to isolated lagerstroemin is limited.

How it works

Lagerstroemin and related tannins from banaba have shown insulin-like activity in cell and animal studies, including activation of glucose transporters and improved glucose uptake into cells. Preclinical work suggests it may complement the action of insulin and lower blood glucose modestly. Most human banaba studies have focused on the whole leaf extract rather than isolated lagerstroemin. Clinical evidence for isolated lagerstroemin is limited.

Dosage

Not standardized for isolated lagerstroemin. Banaba leaf extracts are typically dosed at 32-48 mg of standardized extract (1% corosolic acid) two to three times daily.

When and how to take it

Banaba extracts (containing lagerstroemin and corosolic acid) are typically taken with carbohydrate-containing meals for blood-glucose support.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Banaba leaf extract

Whole-extract form used in most studies.

Contains lagerstroemin plus corosolic acid and other tannins.

Safety

Generally well tolerated in studies of banaba extract. High doses may modestly lower blood glucose, with risk of hypoglycemia if combined with diabetes medications.

Who should be cautious

Use carefully if on insulin or oral hypoglycemics. Avoid in pregnancy and breastfeeding without medical advice. Stop before surgery.

Interactions

May add to the effect of antidiabetic medications. Monitor blood glucose if combining.

Frequently asked questions

Is lagerstroemin the same as corosolic acid?⌄

No. Both are active compounds in banaba leaf, but they are structurally different. Corosolic acid is a triterpene; lagerstroemin is an ellagitannin.

Will lagerstroemin treat my diabetes?⌄

Banaba extract has shown small effects on glucose in clinical studies. It should not replace prescription diabetes medication; consult your clinician about complementary use.

References

Lagerstroemin on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Lagerstroemin (PubMed search) — PubMed link

Track Lagerstroemin with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

Coming to App Store
Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.