Japanese Kadsura

BotanicalBest with a meal

What is it

Japanese kadsura (Kadsura japonica) is a woody vine in the Schisandra family native to East Asia. The stem, root, and fruit are used in traditional Asian medicine for digestive and reproductive concerns.

How it works

Kadsura species contain lignans, triterpenes, and other phenolic compounds. Related species (such as Kadsura coccinea and Schisandra chinensis) have been studied more extensively for adaptogenic, hepatoprotective, and anti-inflammatory activity. Clinical evidence specific to Kadsura japonica is limited. Effects are inferred from related species and from in vitro work on isolated lignans.

Dosage

There is no established daily intake recommendation. Traditional preparations vary widely by region.

When and how to take it

There is no established timing guidance. Herbal extracts are typically taken with meals.

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Kadsura japonica extract

Used in regional Asian herbal blends; standardization is uncommon.

Lignan absorption variable.

Safety

Sparse modern safety data. Traditional use suggests reasonable tolerance, but concentrated extracts have not been well studied.

Who should be cautious

Avoid in pregnancy, breastfeeding, and in people with liver disease. Use caution if taking prescription medications metabolized by the liver.

Interactions

Theoretical interactions with CYP450-metabolized drugs given that related lignan-rich Schisandra species can affect liver enzymes. Caution with prescription medications.

Frequently asked questions

Is Japanese kadsura related to Schisandra?⌄

Yes. Both are in the Schisandraceae family and share some lignan compounds, though they are different species with different traditional uses.

Is it safe?⌄

Specific safety data is limited. Avoid in pregnancy and consult a clinician if you have liver disease or take prescription medications.

References

Japanese Kadsura on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Japanese Kadsura (PubMed search) — PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.