Halostachine

PhytochemicalAlkaloidBest in the morning

What is it

Halostachine (N-methylphenylethanolamine) is a sympathomimetic alkaloid originally identified in Halostachys plants and used in some pre-workout and weight-loss supplements as a stimulant.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Stimulant / thermogenic effect

Mixed Evidence

Animal data suggest stimulant and thermogenic activity; high-quality human evidence is lacking.

How it works

Halostachine acts as a beta-adrenergic agonist with mild stimulant and thermogenic effects in animal studies. It is structurally related to ephedrine and synephrine. Human safety and efficacy data are limited; most supplement use is based on extrapolation from related sympathomimetics, and regulatory status varies.

Dosage

There is no established safe dose. Supplement labels list amounts up to tens of milligrams per serving, often combined with other stimulants. DSLD does not provide a median dose for this entry.

When and how to take it

If used, take earlier in the day to avoid sleep disturbance. Avoid stacking with other stimulants.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Halostachine HCl

Most often included in stimulant supplement blends.

Orally active sympathomimetic salt.

Safety

As a sympathomimetic, side effects can include elevated heart rate, blood pressure, jitteriness, headache, and nausea. Long-term safety in humans is not well established. Banned for athletes in some sports.

Who should be cautious

Avoid in hypertension, cardiovascular disease, anxiety disorders, thyroid disease, pregnancy, breastfeeding, and in adolescents.

Interactions

Avoid combining with caffeine, yohimbine, MAOIs, and prescription stimulants. Additive cardiovascular effects with other sympathomimetics.

Frequently asked questions

Is halostachine safe?⌄

Human safety data are limited. As a sympathomimetic it carries cardiovascular and psychological side-effect risk, especially when combined with other stimulants.

Is it banned by sports organizations?⌄

Many sports anti-doping bodies prohibit non-specified stimulants; check current WADA and sport-specific lists.

References

Halostachine on Wikidata — Wikidata link

Halostachine (ChEBI:167510) — ChEBI link

Halostachine (PubChem CID 6950649) — PubChem link

Halostachine on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Halostachine (PubMed search) — PubMed link

Track Halostachine with Pilora

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.