Galangin

PhytochemicalFlavonoid

What is it

Galangin is a flavonol found in galangal (Alpinia officinarum) and propolis. It is studied preclinically for anti-inflammatory, antimicrobial, and anti-cancer effects.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Anti-inflammatory / anti-cancer (preclinical)

Mixed Evidence

Cell and animal data are interesting; human clinical evidence is essentially absent.

How it works

Galangin shows antioxidant activity, inhibits NF-kB signaling, modulates several CYP enzymes, and demonstrates anti-tumor activity in cell models. Oral bioavailability in humans is low and rapidly conjugated. Human clinical data on isolated galangin are minimal.

Dosage

Not commonly dosed as an isolated supplement. Galangal extracts and propolis products provide the main real-world exposure.

When and how to take it

Follow product-specific instructions.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Propolis or galangal extract

Practical real-world source.

Provides galangin in a mixed-flavonoid matrix.

Safety

Limited human safety data. Propolis (a richer source) is generally well tolerated but can cause allergic reactions in people sensitive to bee products.

Who should be cautious

Bee product allergy (avoid propolis-based products). Pregnancy data are limited.

Interactions

May inhibit certain CYP enzymes at high doses; clinical relevance is unclear.

Food sources

Galangal (1 inch fresh)

Amount
moderate galangin content
%DV
—

Propolis

Amount
rich flavonol source
%DV
—

Frequently asked questions

What is galangin?⌄

A flavonol from galangal and propolis with preclinical anti-inflammatory and anti-tumor activity.

Should I take a galangin supplement?⌄

Stand-alone galangin lacks human evidence. Whole-food galangal or propolis is the practical choice.

References

Galangin on Wikidata — Wikidata link

Galangin (ChEBI:5262) — ChEBI link

Galangin (PubChem CID 5281616) — PubChem link

Galangin on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Galangin (PubMed search) — PubMed link

Track Galangin with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.