Euglena gracilis

Botanical

What is it

Euglena gracilis is a single-celled freshwater microorganism that combines features of plants and animals. It is a rich source of paramylon, a unique beta-1,3-glucan stored as granules, and is sold as 'BetaVia' and similar branded ingredients for immune support.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Upper respiratory tract infections

Good Evidence

Small randomized trials of Euglena gracilis paramylon products suggest modest reductions in cold and flu symptom incidence or duration.

How it works

Paramylon (beta-1,3-glucan) interacts with innate immune receptors (Dectin-1, CR3) on macrophages and other immune cells, modulating cytokine signaling. Small clinical studies of paramylon-containing Euglena have explored effects on upper respiratory infections and inflammation markers.

Dosage

Typical supplement doses range from 100-500 mg/day of Euglena gracilis powder, often standardized to a percentage of paramylon.

When and how to take it

Take with or without food. Consistent daily intake is typical in clinical studies.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Euglena gracilis powder (fermentate)

Commercially available as BetaVia and similar branded ingredients.

Beta-1,3-glucan acts on gut-associated immune cells

Safety

Generally well tolerated in available human studies. Some users report mild gastrointestinal symptoms. Long-term safety data are still accumulating.

Who should be cautious

Use caution in autoimmune disease and during immunosuppressive therapy. Pregnancy and breastfeeding safety data are limited.

Interactions

No significant drug interactions established. Possible additive immune effects with immunomodulatory medications.

Frequently asked questions

What is paramylon?⌄

A linear beta-1,3-glucan unique to Euglena, stored as crystalline granules. It is the main active component of Euglena supplements.

Is Euglena safe?⌄

Generally well tolerated at typical supplement doses. Long-term data are still accumulating.

References

Euglena gracilis on Wikidata — Wikidata link

Euglena gracilis on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Euglena gracilis (PubMed search) — PubMed link

Track Euglena gracilis with Pilora

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.