Elephant Vine

BotanicalBest with a meal

What is it

Elephant vine likely refers to a tropical climbing plant such as Cissus quadrangularis (also called bone-setter or hadjod), though label use of 'elephant vine' is inconsistent across products.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Joint and bone support (likely Cissus)

Limited Evidence

Small clinical trials of Cissus quadrangularis suggest joint comfort and possibly bone healing support. Evidence for other 'elephant vines' is uncertain due to identification issues.

How it works

Cissus quadrangularis, the most commonly intended plant, contains ketosteroids, vitamin C, and triterpenes. It is traditionally used for bone healing and joint support. Modern studies suggest it may affect bone metabolism and joint comfort. Because 'elephant vine' is a non-standard common name, exact species identification varies by product, making it difficult to characterize the specific ingredient without label review.

Dosage

Cissus extracts are typically used at 500-3,000 mg/day. Other 'elephant vines' have different dose ranges if species can be confirmed.

When and how to take it

Cissus extracts are typically taken with meals; follow product label.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Plant extract (likely Cissus)

Sold in joint and bone supplements.

Variable depending on species

Safety

Cissus is generally well-tolerated; side effects include occasional GI upset. Quality and species identification of products labeled 'elephant vine' may vary.

Who should be cautious

Avoid in pregnancy and breastfeeding due to limited safety data. Confirm the actual plant species before use.

Interactions

Limited data. Possible additive effects with anti-inflammatory medications.

Frequently asked questions

What plant is 'elephant vine'?⌄

It usually refers to Cissus quadrangularis, but label use varies. Check the Latin name on the product.

Is it the same as the houseplant elephant ear?⌄

No. Elephant ear (Colocasia) is a different plant.

References

Elephant Vine on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Elephant Vine (PubMed search) — PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.