Dotriacontanol

Fatty-acidPolicosanolBest with a meal

What is it

Dotriacontanol (1-dotriacontanol) is a 32-carbon long-chain primary alcohol present as a minor component in policosanol blends from sugar cane or rice wax.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Policosanol component

Mixed Evidence

Cuban trials of policosanol suggested benefit; independent trials have not replicated. Isolated dotriacontanol has not been studied.

How it works

As a component of policosanol, dotriacontanol may contribute to the overall mixture's purported cholesterol-lowering or platelet effects, though independent replication of policosanol benefits has been negative. There are no isolated dotriacontanol clinical trials.

Dosage

No RDA. Not sold individually.

When and how to take it

WHEN: With meals. HOW: As part of policosanol product.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Within policosanol blend

Not sold as a standalone.

Long-chain alcohols are poorly absorbed.

Safety

Considered safe as part of policosanol blends at typical doses.

Who should be cautious

Limited pregnancy data.

Interactions

No significant interactions reported.

Food sources

Plant waxes (trace)

Amount
n/a
%DV
—

Frequently asked questions

Why list dotriacontanol separately?⌄

It appears on supplement facts panels for policosanol-based products; this entry documents the same.

References

Dotriacontanol on Wikidata — Wikidata link

Dotriacontanol on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Dotriacontanol (PubMed search) — PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.