Dendroxine

PhytochemicalAlkaloid

What is it

Dendroxine is a sesquiterpene alkaloid identified in the orchid genus Dendrobium, particularly Dendrobium nobile, used in traditional Chinese medicine.

How it works

Pharmacological studies of Dendrobium alkaloids in cell and animal models have explored effects on inflammation, blood glucose, and neuronal activity. Specific human research on isolated dendroxine is lacking, so its mechanism in supplements cannot be characterized with confidence.

Dosage

No standardized intake. Supplements typically supply whole Dendrobium extracts standardized to a percentage of total alkaloids rather than isolated dendroxine.

When and how to take it

No formal timing guidance. Follow label directions.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Dendrobium extract

Marketed mainly as whole-extract products; isolated dendroxine is uncommon.

Alkaloid content varies by species, plant part, and extraction

Safety

Limited published human safety data for isolated dendroxine. Dendrobium extracts have been associated with reports of contamination and adulteration in sports nutrition products; choose verified sources.

Who should be cautious

Avoid in pregnancy, breastfeeding, and in children. People sensitive to stimulants should be cautious with Dendrobium-based products, as some have been adulterated with stimulant compounds.

Interactions

No significant interactions reported in available literature.

Frequently asked questions

What is dendroxine?⌄

A sesquiterpene alkaloid found in Dendrobium orchids, used in traditional Chinese herbal preparations.

Is it safe?⌄

Specific human safety data are sparse. Dendrobium-containing products have sometimes been adulterated; verify product quality before use.

References

Dendroxine on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Dendroxine (PubMed search) — PubMed link

Track Dendroxine with Pilora

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.