Evidence-based·Last reviewed May 30, 2026·How we grade evidence

Danshen

Botanical

Useful mainly for people exploring a traditional cardiovascular adjunct under medical supervision.

Quick decision guide

May help most

people exploring a traditional cardiovascular adjunct under medical supervision

Common dosing range

9–15 g/day dried root as a decoction; extracts vary by product

When to expect effects

Weeks

Watch out for

Raises bleeding risk and can increase INR with warfarin

What is it

Danshen (Salvia miltiorrhiza) is a perennial flowering plant whose red roots are widely used in traditional Chinese medicine for cardiovascular conditions. It is sometimes called 'red sage' or 'Chinese salvia.'

Is it worth it for you?

Use this as a quick fit check, not a diagnosis.

Worth considering if

You want a traditional cardiovascular adjunct alongside standard care
You are not on anticoagulants or antiplatelets
You will coordinate use with a cardiologist

Probably skip if

You take warfarin, aspirin, or other blood thinners
You are approaching surgery
You expect oral capsules to match the injectable hospital data

Evidence at a glance

cardiovascular support

Limited Evidence
Effect
Modest
Best fit
adults with ischemic heart disease using it as an adjunct to standard therapy
Time
Weeks

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

cardiovascular support

Disease adjunct
Limited Evidence

Danshen's tanshinones and salvianolic acids produce vasodilation, antiplatelet, and anti-inflammatory effects, and it is widely used in China for ischemic heart disease and stroke, mainly as injectable formulations. Evidence for oral supplements is more limited and suggests only modest cardiovascular benefit, and trial quality is variable. It is one of the more studied TCM herbs, but oral-supplement data do not establish hard-outcome benefit.

Effect size
Modest
Time to effect
Weeks
Best fit
adults with ischemic heart disease using it as an adjunct to standard therapy
Less likely
healthy people seeking prevention

Bottom line: A traditional cardiovascular adjunct with modest oral evidence; the strongest data come from injectable forms not used as supplements.

Evidence is mixed

Robust findings derive largely from injectable preparations and Chinese-language trials of mixed quality, limiting how far they extend to oral supplements.

How it works

Danshen contains tanshinones (lipid-soluble diterpenes) and salvianolic acids (water-soluble polyphenols). Both classes show cardiovascular activity in laboratory and animal studies: vasodilation, antiplatelet effects, anti-inflammatory and antifibrotic actions. Danshen is widely used in China for ischemic heart disease and stroke, often as injectable formulations. Oral supplement evidence is more limited but suggests modest cardiovascular benefits. The herb is one of the more clinically studied TCM herbs.

How to take it

1. Typical dose
9–15 g/day dried root as a decoction; standardized extracts per product labeling
2. Timing
Usually divided into 2–3 doses daily
3. With food
With water; either with or between meals
4. How long to try
Several weeks to assess; ongoing use only under supervision

What to track

blood pressure
any unusual bruising or bleeding
GI tolerance

2 commercial forms

Compare the main delivery options and what they’re best suited for.

Dried root (decoction)

Traditional preparation.

Water extraction captures salvianolic acids.

Standardized extract

Modern supplement form.

Concentrated tanshinone and salvianolic acid content.

Safety

Know the common side effects, key cautions, and who should avoid it.

Common side effects

GI upsetdry mouth

Serious risks

  • increased bleeding risk, especially with anticoagulants

Who should avoid it

  • people on anticoagulant or antiplatelet drugs without supervision
  • those approaching surgery
  • pregnant or breastfeeding women

Pregnancy & breastfeeding

Use with caution and avoid without medical supervision; safety in pregnancy and breastfeeding is not established.

Interactions

warfarinMajor

can increase INR and bleeding risk

antiplatelets (aspirin, clopidogrel)Moderate

additive bleeding risk

CYP enzyme substratesModerate

may alter metabolism of co-administered drugs

Documented interactions

Choosing a product

What to look for on the label — and what to be skeptical of.

Look for

species identified as Salvia miltiorrhiza
tanshinone or salvianolic acid standardization
third-party testing

Be skeptical of

reverses heart disease
replaces prescribed cardiac medication

Frequently asked questions

Can I take danshen with my blood thinner?

No, not without medical supervision. Danshen significantly increases bleeding risk with warfarin and other anticoagulants.

References by claim

cardiovascular support

Jia et al., 2017PubMed (2017) link

Luo et al., 2015PubMed (2015) link

Track Danshen with Pilora

Set up dose reminders, check interactions, and join the community in the Pilora iPhone app.

Coming to App Store
Evidence-based·Last reviewed May 30, 2026·Evidence current as of May 30, 2026·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.