Chlorophyllase

Enzyme

What is it

Chlorophyllase is a plant enzyme that catalyzes the hydrolysis of chlorophyll into chlorophyllide and phytol. It is produced during plant senescence and is used industrially in the production of chlorophyll derivatives such as chlorophyllin.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Industrial / processing role

Mixed Evidence

Functions as a processing enzyme; no demonstrated therapeutic human benefit.

How it works

In food and supplement processing, chlorophyllase facilitates conversion of native chlorophyll into water-soluble forms used as colorants and ingredients. Chlorophyllase itself is a processing aid rather than a therapeutic ingredient with established human pharmacology. Ingested chlorophyllase is degraded by gastrointestinal proteases like other dietary protein, with no characterized systemic enzymatic activity in humans.

Dosage

There is no therapeutic dose. Chlorophyllase appears as a manufacturing enzyme rather than as a labeled supplement active.

When and how to take it

Not applicable as an active ingredient.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Plant or microbial enzyme preparation

Used in chlorophyll derivative manufacturing.

Not orally bioactive in humans.

Safety

Considered safe as a processing aid. As a protein, there is a theoretical allergy potential.

Who should be cautious

No specific cautions beyond general allergy considerations.

Interactions

No clinically significant interactions documented.

Frequently asked questions

Will chlorophyllase 'detox' my body?⌄

No. There is no clinical evidence that orally ingested chlorophyllase has detoxification effects in humans.

References

Chlorophyllase on Wikidata — Wikidata link

Chlorophyllase on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Chlorophyllase (PubMed search) — PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.