Caribbean Grape

BotanicalBest with a meal

What is it

Caribbean grape (Vitis tiliafolia) is a wild grape species native to the Caribbean and Central America. The stem and other plant parts have a folk-medicine history, particularly for urinary and joint complaints.

How it works

Like other Vitis species, Caribbean grape contains polyphenols including resveratrol and various flavonoids. These compounds have antioxidant and anti-inflammatory activity in cell-culture systems. Human clinical evidence specific to Vitis tiliafolia is limited. Effects in people are inferred from related grape and resveratrol studies rather than direct trials of this species.

Dosage

There is no established daily intake recommendation. Supplement labels vary widely. Follow product label guidance.

When and how to take it

No established timing guidance. Herbal extracts are typically taken with meals.

1 commercial form

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Vitis tiliafolia stem extract

Used in regional Caribbean herbal blends, often for urinary or joint support.

Polyphenol absorption variable; standardization not common.

Safety

Generally well tolerated as a traditional remedy. Concentrated extracts have not been extensively studied. Avoid in pregnancy due to limited safety data.

Who should be cautious

Avoid in pregnancy and breastfeeding due to lack of safety data. Use caution if taking anticoagulant or antiplatelet medications.

Interactions

Theoretical interactions with anticoagulants are possible based on polyphenol content. No specific clinically significant interactions have been formally reported.

Frequently asked questions

Is Caribbean grape the same as table grapes?⌄

It is a wild grape species native to the Caribbean. The compounds overlap with common grapes but the human evidence base for the wild species is much smaller.

What is it used for traditionally?⌄

Folk uses focus on urinary tract and joint complaints. Modern clinical evidence for these uses is limited.

References

Caribbean Grape on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Caribbean Grape (PubMed search) — PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.