Campsiandra angustifolia

BotanicalBest taken away from food

What is it

Campsiandra angustifolia (cumandra, cumaru) is an Amazonian tree whose bark is used in traditional Indigenous medicine for malaria, fever and inflammation.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Malaria / fever (traditional)

Mixed Evidence

Indigenous Amazonian use; lacks rigorous clinical evidence.

How it works

The bark contains tannins, alkaloids and phenolic compounds with reported antiparasitic and anti-inflammatory activity in preclinical studies. Specific bioactive constituents are still being characterized. Human clinical evidence is absent in modern literature; traditional use is the main basis for current popularity.

Dosage

No established RDA. Traditional preparations use bark decoctions in variable amounts.

When and how to take it

Traditional bark teas are taken between meals or as needed.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Bark extract

Traditional decoctions.

Variable.

Safety

Limited modern safety data. Tannin content may cause stomach upset; alkaloids could theoretically cause cardiovascular or neurological effects.

Who should be cautious

Avoid in pregnancy and breastfeeding due to lack of data. Use cautiously with chronic medication regimens.

Interactions

No significant interactions documented.

Frequently asked questions

Is cumandra bark safe?

Limited modern data. Traditional use suggests short-term tolerance.

Is it effective for malaria?

Traditional claim, but proven antimalarial drugs are the appropriate medical treatment.

References

Campsiandra angustifolia on WikidataWikidata link

Campsiandra angustifolia on NIH DSLD (US supplement label database)NIH Dietary Supplement Label Database link

Research on Campsiandra angustifolia (PubMed search)PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.