Calcium Potassium Phosphate Citrate

MineralCalciumBest with a meal

What is it

Calcium potassium phosphate citrate (often as the trademarked Calci-K) is a multi-mineral complex providing calcium, potassium, phosphorus, and citrate together in a single chelated form, marketed for bone and kidney support.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Bone health / kidney stone prevention

Limited Evidence

Combined minerals support bone matrix; citrate helps protect against calcium oxalate stones. Specific clinical data for this exact branded combination are limited but consistent with established roles of components.

How it works

The combined complex provides minerals important for bone matrix (calcium, phosphorus) along with potassium and citrate, both of which support urinary alkalinization and may reduce stone formation. Citrate forms of calcium are generally well-absorbed; potassium citrate has prescription use to prevent calcium oxalate kidney stones. This combination form is designed to deliver bone-supportive minerals while also providing the citrate that may protect against kidney stone formation.

Dosage

Doses vary by product; typical Calci-K formulations deliver 200-500 mg of calcium with proportional amounts of other minerals per dose.

When and how to take it

WHEN: With meals (calcium absorption is improved). HOW: With water and food; separate from thyroid medications and certain antibiotics by 2-4 hours.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Calci-K (Albion)

Branded multi-mineral complex.

Mineral chelate combining calcium, potassium, phosphorus, and citrate.

Safety

Generally tolerated. GI side effects (constipation, gas) are possible with calcium supplements. Potassium content should be considered in people on potassium-restricted diets or potassium-sparing medications.

Who should be cautious

Caution with kidney disease (potassium and phosphorus), hyperkalemia risk, and certain heart conditions. Discuss with clinician if on potassium-affecting medications.

Interactions

Potassium may interact with potassium-sparing diuretics (spironolactone, eplerenone), ACE inhibitors, and ARBs (additive potassium retention). Calcium can interfere with absorption of certain antibiotics (tetracyclines, quinolones) and thyroid medications.

Frequently asked questions

Is this safer than taking minerals separately?

Convenience and balanced delivery are the main advantages. Safety and effectiveness depend on appropriate dosing and your overall mineral status, not the combined form alone.

References

Calcium Potassium Phosphate Citrate on NIH DSLD (US supplement label database)NIH Dietary Supplement Label Database link

Research on Calcium Potassium Phosphate Citrate (PubMed search)PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.