Beta-Methylphenylethylamine

PhytochemicalPhenethylamine

What is it

Beta-methylphenylethylamine (BMPEA, N-methyl-beta-phenylethylamine) is a synthetic stimulant compound related to amphetamine. It has appeared as an undeclared ingredient in some 'pre-workout' and weight-loss supplements, often falsely labeled as Acacia rigidula extract.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Stimulant effects

Mixed Evidence

Pharmacologically a stimulant but safety concerns outweigh any acute effects.

How it works

BMPEA acts as a sympathomimetic stimulant, releasing norepinephrine and dopamine. Effects include increased heart rate, blood pressure, and CNS stimulation - similar to but weaker than amphetamine.

Dosage

Not legally permitted in dietary supplements. We do not recommend any dose.

When and how to take it

Not applicable - we do not recommend use.

1 commercial form

Compare the main delivery options and what they’re best suited for.

BMPEA HCl

Illegally added to some 'natural' supplements.

Orally bioavailable

Safety

FDA has stated BMPEA is not a lawful dietary ingredient. Reported adverse effects include hypertension, palpitations, anxiety, and increased stroke risk. WADA and NCAA prohibit it.

Who should be cautious

Should be avoided by all populations. Particularly dangerous in cardiovascular disease, hypertension, anxiety, pregnancy/lactation. Athletes face sanctions.

Interactions

Significant interactions with MAOIs, SSRIs, sympathomimetics, and cardiovascular medications. Risk of serotonin syndrome and hypertensive crisis.

Frequently asked questions

Is BMPEA legal?⌄

No. FDA has stated it is not a lawful dietary ingredient. Avoid products containing BMPEA.

Is BMPEA in 'Acacia rigidula' extracts?⌄

Some products labeled as containing Acacia rigidula have been found to contain BMPEA, though it is not naturally occurring in the plant.

References

Beta-Methylphenylethylamine on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Beta-Methylphenylethylamine (PubMed search) — PubMed link

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.