Alisma

Botanical

What is it

Alisma (Alisma orientale, Asian water plantain), known as ze xie in TCM, is an aquatic perennial whose rhizome is used in traditional Chinese medicine, particularly for fluid retention and urinary complaints.

Evidence for 1 use

AI-assisted evidence assessment — talk to your doctor before relying on any single supplement.

Fluid balance / urinary support (traditional use)

Mixed Evidence

Strong TCM tradition for diuretic and fluid-related uses. Modern clinical evidence is limited.

How it works

Alisma rhizomes contain triterpenes (alisol A and B) and polysaccharides. Laboratory studies suggest diuretic activity and modest lipid-lowering effects in animal models. In TCM, alisma is used to 'drain dampness' and is a common component of formulas for edema, urinary symptoms, and cholesterol concerns. Most clinical evidence is from TCM combination formulas rather than alisma alone. Modern controlled trials are sparse.

Dosage

Traditional TCM doses are 6-15 g of dried rhizome daily as a decoction.

When and how to take it

WHEN: 2-3 times daily as part of TCM formulas. HOW: As a decoction or in capsules with water.

1 commercial form

Compare the main delivery options and what they’re best suited for.

Dried rhizome / decoction

Traditional preparation.

Triterpenes and water-soluble compounds extracted by simmering.

Safety

Generally safe at traditional doses. Side effects can include excessive urination and (rarely) electrolyte disturbances with prolonged use. Long-term safety data are limited.

Who should be cautious

Avoid during pregnancy and breastfeeding. Caution with kidney disease, electrolyte abnormalities, and diuretic use. Discuss with a clinician.

Interactions

May enhance effects of diuretics. Theoretical interaction with lithium (related to diuresis) and antihypertensives.

Frequently asked questions

Is alisma a strong diuretic?⌄

It has mild diuretic activity in animal studies. Its effect in humans is variable and less potent than pharmaceutical diuretics.

References

Alisma on Wikidata — Wikidata link

Alisma on NIH DSLD (US supplement label database) — NIH Dietary Supplement Label Database link

Research on Alisma (PubMed search) — PubMed link

Track Alisma with Pilora

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Evidence-based·How we grade evidence

Disclaimer: These statements have not been evaluated by the FDA. This page is educational, not a substitute for personalized medical advice. Evidence grades are AI-assisted assessments — talk to your doctor before starting any new supplement, especially if you’re pregnant, breastfeeding, on medications, or managing a chronic condition.