Cannabis Interactions

1 documented interaction — 1 warning, 0 beneficial pairs.

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Interaction warnings

Cannabis + ssris

Cannabis cannabinoids inhibit CYP2C19, CYP2C9, and CYP3A4, raising plasma levels of SSRIs such as sertraline, citalopram, and escitalopram. Cannabinoids also modulate serotonin signaling, and case reports describe serotonin syndrome precipitated by high-potency cannabis in patients on SSRIs.

Related ingredients

Ingredients commonly checked alongside Cannabis.

Ssris(1)

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