withania somnifera
2 interactions related to withania somnifera
caffeine + ashwagandha
Ashwagandha is an adaptogen that lowers cortisol and reduces perceived anxiety; caffeine is a stimulant that raises cortisol and can increase anxiety. Taking them together can blunt caffeine's anxiety and jitter side effects while preserving its alertness benefit, but ashwagandha may also slightly dampen caffeine's peak stimulant effect.
caffeineashwagandhaadaptogencortisolstressanxietywithania somniferasleepjitterssupplements
levothyroxine + ashwagandha
Ashwagandha (Withania somnifera) can increase serum T3 and T4 and lower TSH, effectively adding to the thyroid hormone effect of levothyroxine. Case reports describe patients on stable levothyroxine who developed thyrotoxicosis and even painless thyroiditis after starting ashwagandha.
levothyroxineashwagandhawithania somniferathyroidhyperthyroidismthyrotoxicosistshadaptogen