1 interaction related to varenicline
Varenicline (Chantix/Champix) is a partial agonist at the alpha4-beta2 nicotinic acetylcholine receptor — the same receptor nicotine targets. It makes smoking less rewarding, so it is started before your quit date and you may keep smoking briefly at first. Combining varenicline with nicotine replacement (patches, gum) can raise quit rates but increases side effects such as nausea, headache, vomiting, and dizziness.