1 interaction related to valerian root
Valerian and alcohol both act on the GABA-A receptor system and are central nervous system depressants. Combining them carries a recognized possibility of additive sedation — more drowsiness, slower reactions, and impaired coordination than either alone. Most of this rests on shared mechanism and expert caution rather than large human outcome trials, but the practical concern is real: impaired driving and falls, particularly in older adults.