ulcer
3 interactions related to ulcer
alcohol + naproxen
Naproxen is a long-acting NSAID that weakens the stomach's protective lining and blunts platelet function. Adding alcohol stacks several forms of damage on top of each other, and naproxen's long action keeps that interaction window open well beyond the last dose.
alcohol + aspirin
Aspirin and alcohol both damage the gastric lining and impair clotting; used together they raise the risk of upper gastrointestinal bleeding, with risk rising as alcohol intake and aspirin use increase.
alcohol + ibuprofen
Alcohol and ibuprofen each irritate the stomach lining and impair platelet function, and combining them raises the risk of gastrointestinal bleeding and ulcers. Both also stress the kidneys — ibuprofen reduces renal blood flow while alcohol drives dehydration — which can add up to acute kidney injury, especially in older adults or people with existing kidney problems.