1 interaction related to tofu
Tofu is one of the most concentrated sources of soy protein in the diet. Soy protein binds levothyroxine in the gut and reduces how much of the drug is absorbed, and case reports describe TSH rising when soy-heavy foods like tofu are added to a previously stable levothyroxine regimen. The effect is modest in most adults but clinically relevant in sensitive patients, and it is managed by timing.