1 interaction related to thromboembolism
Observational studies dating back to the 1970s have found that women taking combined oral contraceptives tend to have somewhat lower serum magnesium levels than non-users, likely through estrogen-related shifts in how the body distributes and excretes magnesium. This is a nutritional observation, not a contraceptive-failure risk. Magnesium does not reduce the pill's effectiveness, and links between low magnesium and pill side effects or clotting risk remain theoretical rather than proven.