theobromine
2 interactions related to theobromine
chocolate + adenosine
Caffeine and theobromine from chocolate are competitive antagonists at A1 and A2A adenosine receptors. When intravenous adenosine is used for cardiac stress testing or to terminate supraventricular tachycardia, recent methylxanthine intake can blunt its effects and lead to a falsely negative test or failure to convert the arrhythmia.
chocolateadenosineregadenosoncardiac stress testcaffeinetheobrominemethylxanthineSVTnuclear stress test
hot chocolate + sleep medications
Hot chocolate contains caffeine and theobromine, methylxanthines that antagonize adenosine receptors. Because zolpidem, eszopiclone, benzodiazepines, and other sedatives work in part by amplifying inhibitory neurotransmission, evening hot chocolate can partially blunt their sedative effect and worsen sleep onset and maintenance.
hot chocolatesleep medicationzolpidemambienbenzodiazepinecaffeinetheobromineinsomniaadenosine