supplement-interaction
3 interactions related to supplement-interaction
cayenne + warfarin
Capsaicin, the active constituent in cayenne (Capsicum), has been reported to potentiate the anticoagulant effect of warfarin, theoretically through additive effects on platelet aggregation and possible enhancement of warfarin absorption or activity, increasing bleeding risk.
cinnamon + warfarin
Cassia cinnamon contains coumarin, a natural compound with anticoagulant activity that may potentiate warfarin and increase bleeding risk. Case reports describe elevated INR and bleeding when cinnamon supplements were added to stable warfarin therapy.
fenugreek + warfarin
Fenugreek (Trigonella foenum-graecum) contains coumarin-related compounds and has documented in vitro anticoagulant activity. A published case report describes elevated INR when boldo-fenugreek was added to stable warfarin therapy, with INR normalizing on discontinuation and rising again on rechallenge.