1 interaction related to seroquel
Quetiapine is metabolized primarily by CYP3A4. Grapefruit juice irreversibly inhibits intestinal CYP3A4 and can substantially increase quetiapine plasma concentrations. A published case report describes quetiapine toxicity in a young woman who consumed a large volume of grapefruit juice over a single day while on a stable dose, with sedation, low blood pressure, and ECG changes that resolved once the juice was stopped.
