1 interaction related to senescence
Fisetin and quercetin are structurally related flavonols with overlapping but distinct senolytic and anti-inflammatory mechanisms. Fisetin was identified in a Mayo Clinic screen as the most potent natural senolytic, while quercetin has been clinically tested as part of the dasatinib + quercetin senolytic combination, and the two together broaden the senolytic and antioxidant coverage.