salt substitute

3 interactions related to salt substitute

lisinopril + salt substitutes

Most popular salt substitutes replace sodium chloride with potassium chloride, delivering a meaningful potassium load with every shake. Lisinopril, an ACE inhibitor, reduces the kidney's ability to excrete potassium. Used together, this combination has caused documented cases of life-threatening hyperkalemia, including emergencies requiring dialysis.

critical
lisinoprilsalt substitutepotassium chlorideace inhibitorhyperkalemiacardiac arrestblood pressurenosalt

salt substitute + spironolactone

Most salt substitutes replace ordinary table salt with potassium chloride, so they act as concentrated potassium supplements. Spironolactone is a potassium-sparing diuretic that reduces how much potassium the kidneys excrete. Using the two together can drive potassium high enough to cause dangerous, sometimes life-threatening heart rhythm problems (hyperkalemia).

critical
salt substitutespironolactonepotassium chloridehyperkalemiapotassium-sparingdiureticdrug interactionheart

salt substitute + lisinopril

Most salt substitutes replace sodium chloride with potassium chloride, making them a concentrated source of potassium. Lisinopril and other ACE inhibitors lower aldosterone and reduce the kidneys' ability to clear potassium. Used together, they can raise blood potassium to dangerous levels (hyperkalemia), especially in people with reduced kidney function, diabetes, older age, or who take other potassium-raising medicines.

high
salt substitutelisinoprilace inhibitorpotassium chloridehyperkalemiablood pressuredrug interactionkidney