prograf
2 interactions related to prograf
cranberry + tacrolimus
The only human report on cranberry and tacrolimus showed tacrolimus levels falling sharply, not rising; lab studies predict the opposite, so the true direction is genuinely unpredictable. Because tacrolimus has a very narrow therapeutic window, any change in cranberry intake deserves a trough check.
lactobacillus + tacrolimus
Tacrolimus is a calcineurin-inhibitor immunosuppressant used after solid-organ transplant. In immunosuppressed transplant recipients, Lactobacillus probiotic organisms can cross the gut wall and cause bloodstream infection. Published case reports document Lactobacillus rhamnosus bacteremia in renal transplant patients on tacrolimus, and many probiotic strains are intrinsically vancomycin-resistant, making treatment harder.