platelet function
2 interactions related to platelet function
alcohol + ibuprofen
Alcohol and ibuprofen each irritate the stomach lining and impair platelet function, and combining them raises the risk of gastrointestinal bleeding and ulcers. Both also stress the kidneys — ibuprofen reduces renal blood flow while alcohol drives dehydration — which can add up to acute kidney injury, especially in older adults or people with existing kidney problems.
vitamin e + platelet function test
Higher-dose vitamin E (alpha-tocopherol) can inhibit platelet aggregation through a protein kinase C-dependent mechanism, prolonging bleeding times and producing abnormal results on platelet function tests such as the PFA-100, VerifyNow, and light transmission aggregometry. The effect is most pronounced alongside aspirin or other antiplatelet drugs and can complicate a workup for a suspected bleeding disorder.