oxidative stress
3 interactions related to oxidative stress
smoking + vitamin c
Smoking increases oxidative stress and accelerates the metabolic turnover of vitamin C, lowering plasma and leukocyte ascorbic acid levels. The NIH Food and Nutrition Board officially recommends that smokers consume an additional 35 mg of vitamin C daily above the standard RDA.
nac + glutathione
NAC (N-acetylcysteine) provides the rate-limiting cysteine substrate the body uses to synthesize new glutathione intracellularly, while supplemental glutathione directly replenishes the circulating and extracellular pool. The two work through complementary upstream-and-downstream mechanisms to support antioxidant defense and phase II liver detoxification.
vitamin e + selenium
Vitamin E and selenium work as complementary antioxidants. Selenium is the cofactor for glutathione peroxidase, which clears lipid peroxides, sparing vitamin E. Vitamin E in turn prevents lipid peroxidation, reducing demand on the selenium-dependent enzyme.