osteocalcin
2 interactions related to osteocalcin
vitamin d3 + vitamin k2
Vitamin D3 increases calcium absorption and stimulates production of vitamin K-dependent proteins (osteocalcin, matrix Gla protein) that themselves require K2 for activation. Co-supplementation supports bone density and may reduce vascular calcification compared with D3 alone.
vitamin d3vitamin k2mk-7synergybone healthcalciumarterial calcificationosteocalcin
vitamin k2 + calcium
Vitamin K2 activates osteocalcin and matrix Gla protein, which bind calcium and direct it into the bone matrix while keeping it out of arterial walls. Calcium supplementation paired with adequate K2 supports bone density and reduces the risk of misplaced calcium in soft tissue.
vitamin k2calciumsynergybone healthosteocalcinmatrix gla proteinmk-7arterial calcification