1 interaction related to oatp1b1
Rosuvastatin is carried into liver cells by the OATP1B1 transporter. In a laboratory study using human liver-cell cultures, berberine increased OATP1B1 activity and pushed more rosuvastatin into the cells. This is an early, test-tube signal only: there is no human or animal data showing it changes blood levels, cholesterol response, or side-effect risk in real life.