1 interaction related to norco
Hydrocodone and alcohol are both central nervous system depressants. Taken together they cause additive depression of the brainstem breathing centers, which can lead to profound sedation, dangerously slowed or stopped breathing, coma, and death even at otherwise-tolerated opioid doses. Some extended-release hydrocodone formulations can also "dose dump" when combined with alcohol, releasing the dose prematurely. Hydrocodone-acetaminophen products add a separate alcohol-related liver-injury risk.
