milk
2 interactions related to milk
tetracycline + calcium
Calcium binds tightly to tetracycline in the gut, forming an insoluble chelate that cannot be absorbed. Dairy products and calcium supplements can reduce tetracycline absorption by 50 to 90 percent, often dropping serum levels below the threshold needed to treat infection.
tetracyclinecalciumantibioticchelationabsorptiondairymilksupplement timing
milk + levodopa
Large neutral amino acids in milk protein (especially leucine, isoleucine, and valine) compete with levodopa for the same intestinal and blood-brain barrier transporter (LAT1), reducing levodopa absorption and brain delivery. Patients with Parkinson disease can experience reduced symptom control or motor fluctuations when levodopa is taken with milk or other high-protein meals.
milklevodopaparkinsonproteinamino acidsabsorptionsinemettransporter