1 interaction related to low-sodium diet
Lithium and sodium are handled by the same transporters in the kidney and compete for reabsorption. Eating much less sodium than usual causes the kidneys to hold on to both sodium and lithium, which can push lithium levels up toward toxicity; a sudden large increase in sodium can flush lithium out and drop it below the level needed to control mood. The amount of sodium matters less than keeping it steady.
