lipid peroxidation
2 interactions related to lipid peroxidation
vitamin e + vitamin c
Vitamin C regenerates the active form of vitamin E. After vitamin E neutralizes a lipid free radical and becomes a tocopheroxyl radical, vitamin C donates an electron at the membrane surface to restore it. This recycling loop extends antioxidant capacity at the lipid-water interface of cell membranes. It is a beneficial synergy, not a risk.
vitamin e + selenium
Vitamin E and selenium are complementary antioxidants. Selenium is the cofactor for glutathione peroxidase, which clears lipid peroxides and spares vitamin E, while vitamin E intercepts free radicals in membranes and reduces the demand on the selenium-dependent enzyme. The partnership is well established in animal and mechanistic studies; clinical benefit of the combination in people is more limited.