1 interaction related to latuda
Lurasidone is metabolized almost entirely by the CYP3A4 enzyme, which makes it highly sensitive to CYP3A4 inhibitors. The FDA-approved Latuda prescribing information states that grapefruit and grapefruit juice should be avoided in patients taking lurasidone, because they inhibit CYP3A4 and can raise lurasidone concentrations.